Answer ID 3051
To enable 10 or 12-bit greyscale, no special software configuration in the NVIDIA Control Panel is required. When a grayscale compatible monitor is connected to a supported NVIDIA Quadro card, the NVIDIA driver automatically detects it and immediately switches to packed pixel mode.
The only configuration that is required is to use Display Properties -> Settings -> Advanced to set the greyscale monitor to display at its optimal resolution. Uncheck the Hide modes that this monitor cannot display check box. Select the optimal resolution and Apply.
There is more information on supported Quadro cards, displays, and configuring the optimal resolution here: